Magician under the moonlight
Bill S. Preston, Esq.
Always Beaten To The Punchline. Always.
A magician and a thief. That's Badass
Posts: 15,727
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Post by Magician under the moonlight on Dec 24, 2011 9:58:13 GMT -5
I wish to read the actual paper instead of this news report. As a microbiologist I can tell you that the hardest part of developing a vaccine to HIV is that the virus mutates tremendously from person to person. The only antigen on the virus that is known to not mutate is the protein that binds to the immune cell proteins, which leads to adherence and internalization of the virus. The down side is that you cannot make a vaccine for that antigen because it will be identical to proteins on your own cells. Making a vaccine for that will lead to autoimmune disease. If they have determined that there is another antigen that does not vary between hosts I would love to know that. Guess I need to hit the medical books. Mekes me wonder aboit the efficiency of it. I wonder if they were able to determine the diffetence between the receptors of that antigen and the proteins in out cell. If so, there is still hope, i
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Dr. T is an alien
Patti Mayonnaise
Knows when to hold them, knows when to fold them
I've been found out!
Posts: 31,306
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Post by Dr. T is an alien on Dec 24, 2011 14:43:48 GMT -5
I wish to read the actual paper instead of this news report. As a microbiologist I can tell you that the hardest part of developing a vaccine to HIV is that the virus mutates tremendously from person to person. The only antigen on the virus that is known to not mutate is the protein that binds to the immune cell proteins, which leads to adherence and internalization of the virus. The down side is that you cannot make a vaccine for that antigen because it will be identical to proteins on your own cells. Making a vaccine for that will lead to autoimmune disease. If they have determined that there is another antigen that does not vary between hosts I would love to know that. Guess I need to hit the medical books. Mekes me wonder aboit the efficiency of it. I wonder if they were able to determine the diffetence between the receptors of that antigen and the proteins in out cell. If so, there is still hope, i That would be the hardest thing to do, however. Only the active site is constant on the viral proteins. The rest of the protein is almost truly random, making it so that the protein is completely different from person to person. I suppose that if you really wanted to have sex with Magic Johnson you could make a vaccine for his specific strain, but that vaccine would not work if you were worried about getting infected by one of his infected formers lovers.
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Magician under the moonlight
Bill S. Preston, Esq.
Always Beaten To The Punchline. Always.
A magician and a thief. That's Badass
Posts: 15,727
|
Post by Magician under the moonlight on Dec 24, 2011 15:18:03 GMT -5
Mekes me wonder aboit the efficiency of it. I wonder if they were able to determine the diffetence between the receptors of that antigen and the proteins in out cell. If so, there is still hope, i That would be the hardest thing to do, however. Only the active site is constant on the viral proteins. The rest of the protein is almost truly random, making it so that the protein is completely different from person to person. I suppose that if you really wanted to have sex with Magic Johnson you could make a vaccine for his specific strain, but that vaccine would not work if you were worried about getting infected by one of his infected formers lovers. Well it was just a suggestion. I studied in microbiology and I know that Similar cels and viruses have some specific receptors. I know it would be hard to identify the ones with are totally different between them, but it may be the only was to have an efficient vaccine. If not, 'like you said, that vaccine may cause an autoimmune disease. BTW, Good to have another microbiologist on board.
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