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Post by Zaq "That Guy" Buzzkill on Dec 20, 2011 23:29:16 GMT -5
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Post by HMARK Center on Dec 20, 2011 23:30:59 GMT -5
Here's hoping.
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Post by Cela on Dec 20, 2011 23:33:33 GMT -5
Patience...
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Post by Michael Coello on Dec 20, 2011 23:38:43 GMT -5
I know it's wrong, but this was the first thing that sprung to mind:
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THE Baldy Kendrick
Dennis Stamp
may be an ursaring, may not.
I hear dem shoutin'.
Posts: 3,895
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Post by THE Baldy Kendrick on Dec 20, 2011 23:42:01 GMT -5
The fact that this even is this close to existing is just absolutely amazing.
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Dr. T is an alien
Patti Mayonnaise
Knows when to hold them, knows when to fold them
I've been found out!
Posts: 31,306
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Post by Dr. T is an alien on Dec 20, 2011 23:43:43 GMT -5
I wish to read the actual paper instead of this news report. As a microbiologist I can tell you that the hardest part of developing a vaccine to HIV is that the virus mutates tremendously from person to person. The only antigen on the virus that is known to not mutate is the protein that binds to the immune cell proteins, which leads to adherence and internalization of the virus. The down side is that you cannot make a vaccine for that antigen because it will be identical to proteins on your own cells. Making a vaccine for that will lead to autoimmune disease.
If they have determined that there is another antigen that does not vary between hosts I would love to know that. Guess I need to hit the medical books.
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Post by BlackoutCreature on Dec 21, 2011 0:23:14 GMT -5
I wish to read the actual paper instead of this news report. As a microbiologist I can tell you that the hardest part of developing a vaccine to HIV is that the virus mutates tremendously from person to person. The only antigen on the virus that is known to not mutate is the protein that binds to the immune cell proteins, which leads to adherence and internalization of the virus. The down side is that you cannot make a vaccine for that antigen because it will be identical to proteins on your own cells. Making a vaccine for that will lead to autoimmune disease. If they have determined that there is another antigen that does not vary between hosts I would love to know that. Guess I need to hit the medical books. Bah, you and your fancy medical jargon. I'll have you know I just recently got an E mail from a fellow who says that he created a working cure for HIV and AIDS from natural herbs locally grown in his village. Unfortunetaly the corrupt Nigerian government keeps preventing him from sharing this with the rest of the world. All he needs is a few thousand dollars to smuggle a sample of the cure outside his country. The kind hearted person I am, I'm trying to get the money together now to help him. Might have to sell a few more of my mothers organs though.
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Sc
Don Corleone
Must think of something witty to put here...
Posts: 1,417
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Post by Sc on Dec 21, 2011 1:28:41 GMT -5
It seems like every year a report on a possible cure for HIV comes out and nothing ever comes of it. I hope this will be different but I doubt it.
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Post by Spankymac is sick of the swiss on Dec 21, 2011 2:08:44 GMT -5
It seems like every year a report on a possible cure for HIV comes out and nothing ever comes of it. I hope this will be different but I doubt it. Well the thing is, it's likely the same story. Scientific research is just slow going, especially in this case.
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jobber2thestars
Hank Scorpio
Buy the Simon System. You'll thank yourself.
Posts: 7,097
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Post by jobber2thestars on Dec 21, 2011 2:21:02 GMT -5
HIV and AIDS have claimed too many lives, and ruined countless others. Let's hope that we finally have a way to defeat this thing after almost thirty years of suffering.
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Post by Clash, Never a Meter Maid on Dec 21, 2011 10:19:46 GMT -5
Hell, the fact that'd we've gotten this far in the fight is reason enough to celebrate a little. It's not over, but it's a significant blow.
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Post by wcw on Dec 21, 2011 12:13:54 GMT -5
Patrice Oneal was right, we will get the AIDS vaccine before we get the cure for any type of cancer. Seriously mankinds desire to f*** raw out does our desire to live.
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Dr. T is an alien
Patti Mayonnaise
Knows when to hold them, knows when to fold them
I've been found out!
Posts: 31,306
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Post by Dr. T is an alien on Dec 23, 2011 13:21:48 GMT -5
Patrice Oneal was right, we will get the AIDS vaccine before we get the cure for any type of cancer. Seriously mankinds desire to f*** raw out does our desire to live. The problem is that cancer can be caused by so many things, including simply aging as your cells can mutate every time they replicate. Granted, things that damage your DNA dramatically increase the odds as many of your DNA repair mechanisms are not perfect. If they were, sometimes they actually would not work at all. As a result, the odds are just in favor of some of your cells mutating in an undesirable manner.
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riseofsetian1981
King Koopa
"I met him fifteen years ago. I was told there was nothing left."
Posts: 10,323
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Post by riseofsetian1981 on Dec 23, 2011 13:27:00 GMT -5
If this is true and the research holds up, then they need to make sure that every individual has access. I just know they'll only make sure that the extremely wealthy have access to the vaccine and the medicine.
Everyone from the extremely rich upper class, to the middle class, and lower class should be able to receive this IF the studies hold true and it completely eradicates the virus.
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Post by BlackoutCreature on Dec 23, 2011 17:07:10 GMT -5
If this is true and the research holds up, then they need to make sure that every individual has access. I just know they'll only make sure that the extremely wealthy have access to the vaccine and the medicine. Everyone from the extremely rich upper class, to the middle class, and lower class should be able to receive this IF the studies hold true and it completely eradicates the virus. Ok, maybe I'm wrong about this, but I'm not familiar with any kind of history of disease vaccines/cures being made unavailable to lower social classes in the US due to costs. Was there some kind of controversy during the early days of the polio or smallpox vaccinations that I've never heard of that would spark this fear of yours?
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Dr. T is an alien
Patti Mayonnaise
Knows when to hold them, knows when to fold them
I've been found out!
Posts: 31,306
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Post by Dr. T is an alien on Dec 23, 2011 17:37:18 GMT -5
If this is true and the research holds up, then they need to make sure that every individual has access. I just know they'll only make sure that the extremely wealthy have access to the vaccine and the medicine. Everyone from the extremely rich upper class, to the middle class, and lower class should be able to receive this IF the studies hold true and it completely eradicates the virus. Ok, maybe I'm wrong about this, but I'm not familiar with any kind of history of disease vaccines/cures being made unavailable to lower social classes in the US due to costs. Was there some kind of controversy during the early days of the polio or smallpox vaccinations that I've never heard of that would spark this fear of yours? Well, prior to vaccinations the way to deal with smallpox was to expose your children to kids that had the less virulent strain of smallpox (there were two strains, one that killed over half of all children that got it and one that killed very few children). This was something that the rich could arrange while the poor could not.
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Post by eukaryote on Dec 23, 2011 19:06:02 GMT -5
well, this is certainly promising news but i'm not sure as to the likelihood of it becoming a reality anytime soon. as someone else mentioned; the aids virus evolves in response to drugs used to combat it - the surviving strains multiply, passing on their drug-resistant genes. this makes it difficult to create a vaccine for it.
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Post by Piccolo on Dec 23, 2011 22:44:20 GMT -5
I wish to read the actual paper instead of this news report. As a microbiologist I can tell you that the hardest part of developing a vaccine to HIV is that the virus mutates tremendously from person to person. The only antigen on the virus that is known to not mutate is the protein that binds to the immune cell proteins, which leads to adherence and internalization of the virus. The down side is that you cannot make a vaccine for that antigen because it will be identical to proteins on your own cells. Making a vaccine for that will lead to autoimmune disease. If they have determined that there is another antigen that does not vary between hosts I would love to know that. Guess I need to hit the medical books. Yeah, if I could mandate anything in science journalism, it would be LINKS. Even if those of us who aren't active scientists don't have the cash to subscribe to every relevant journal out there, we could at least read the abstracts. That said, here's what comes up for Kang CY HIV in PubMed, if anyone's interested: www.ncbi.nlm.nih.gov/pubmed?term=kang%20cy%20hiv
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riseofsetian1981
King Koopa
"I met him fifteen years ago. I was told there was nothing left."
Posts: 10,323
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Post by riseofsetian1981 on Dec 24, 2011 9:24:53 GMT -5
If this is true and the research holds up, then they need to make sure that every individual has access. I just know they'll only make sure that the extremely wealthy have access to the vaccine and the medicine. Everyone from the extremely rich upper class, to the middle class, and lower class should be able to receive this IF the studies hold true and it completely eradicates the virus. Ok, maybe I'm wrong about this, but I'm not familiar with any kind of history of disease vaccines/cures being made unavailable to lower social classes in the US due to costs. Was there some kind of controversy during the early days of the polio or smallpox vaccinations that I've never heard of that would spark this fear of yours? I am not familiar with the polio or smallpox vaccinations that you are speaking of, I will most definitely admit that. What Attack posted in reply to your post was the first I have heard of that situation. I wouldn't say it's a fear per se, more of a concern that a vaccination/possible cure of this magnitude, is not going to be available to everyone equally. Which makes me sad and upset because this will be a major breakthrough should it actually be a cure. But I just have this feeling that only the rich will have access to it, while the middle class, lower class, and near poverty families or individuals will be left suffering from this tragic disease. A big part of me believes they've had the cure for a lot of diseases and they want to share it with a certain type of social and monetary class.
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Post by Piccolo on Dec 24, 2011 9:46:29 GMT -5
Which makes me sad and upset because this will be a major breakthrough should it actually be a cure. But I just have this feeling that only the rich will have access to it, while the middle class, lower class, and near poverty families or individuals will be left suffering from this tragic disease. A big part of me believes they've had the cure for a lot of diseases and they want to share it with a certain type of social and monetary class. To be honest, I think that's the most comforting kind of conspiracy theory... the theory that there's really no problem out there that we can't or haven't solved. It's not human limitation that's holding us back, but some flaw that we could potentially fix... greed, racism, hatred of some kind. If only we could find the evildoers and expose their deeds, we could heal the world. It's a lot easier to find and expose evildoers, after all, than to spend decades at the lab bench trying to come up with a cure. I think it makes us feel better about the helplessness that we experience when we watch people suffering, if we think the only thing that stands in the way of their health and safety are corrupt individuals or corporations. I think the reality of it is much more frustrating, and much more frightening... which is to say, research is a long, slow, and very expensive process, and there are no guarantees that you're going to ever find a cure.
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